Exposure to UV radiation, most commonly from the sun, causes over 95% of skin cancers.
UV radiation is made up of UVA and UVB rays, which can penetrate the dermis and epidermis of the skin, damaging DNA. Whilst the body does its best to repair it, this DNA damage accumulates over time and can lead to cancer growth.
Introducing
RM191A: A second chance to save your skin
As a powerful antioxidant and anti‑inflammatory, RM191A shows compelling results in treating UV radiation (sun) burns. It not only reduces pain but dramatically reduces the amount of cellular and DNA damage.
Tests on human skin have shown that RM191A is most effective when applied both before and after exposure to UV radiation.
Data published in Redox Biology demonstrated RM191A's ability to reduce levels of DNA damage in human skin subjected to solar simulator (UV) radiation.
In this study, UV-induced DNA damage was measured via levels of cyclobutane pyrimidine dimers (CPDs), oxidative DNA damage was measured in the form of 8-oxo-guanine (8-oxoG), and nitrosative DNA damage in the form of 8-nitroguanine (8NGO).
Pre- and post-treatment with RM191A gel showed:
Reduction of
CPD in the epidermis
compared to vehicle
Reduction of
8-OXOG in the epidermis
compared to vehicle
Reduction of
8NGO in the dermis
compared to vehicle